Item Type | Name |
Concept
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Alleles
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Concept
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Amino Acid Sequence
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Concept
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Analysis of Variance
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Concept
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Base Sequence
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Concept
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Genetic Vectors
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Concept
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DNA Mutational Analysis
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Concept
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Genes
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Concept
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Oncogenes
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Concept
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Multigene Family
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Concept
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Models, Molecular
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Concept
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Models, Genetic
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Concept
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Molecular Sequence Data
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Concept
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Molecular Weight
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Concept
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Recombination, Genetic
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Concept
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Molecular Biology
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Concept
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Genes, Intracisternal A-Particle
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Concept
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Regression Analysis
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Concept
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Genes, ras
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Concept
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Cluster Analysis
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Concept
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Transcription, Genetic
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Concept
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Genes, abl
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Concept
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Sequence Homology, Amino Acid
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Concept
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Genetic Variation
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Concept
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Leukemia, Myeloid
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Concept
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Genes, Tumor Suppressor
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Concept
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Leukemia, Myeloid, Acute
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Concept
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Sequence Analysis, DNA
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Concept
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Genes, Reporter
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Concept
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src Homology Domains
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Concept
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Single-Cell Analysis
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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Databases, Genetic
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Concept
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Animals, Genetically Modified
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Concept
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Promoter Regions, Genetic
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Concept
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Molecular Targeted Therapy
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Concept
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Multivariate Analysis
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Concept
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Survival Analysis
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Concept
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Genetic Therapy
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Concept
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Molecular Structure
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Concept
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Genome, Human
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Concept
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Genes, src
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Concept
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Genes, fos
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Concept
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Sequence Analysis, Protein
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Concept
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Genes, erbB-2
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Concept
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Genetic Heterogeneity
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Concept
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Transcriptome
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Concept
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Molecular Sequence Annotation
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Concept
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Tissue Array Analysis
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Concept
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Molecular Typing
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Concept
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Cloning, Molecular
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Concept
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Enhancer Elements, Genetic
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Concept
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Genetic Testing
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Concept
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Translocation, Genetic
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Concept
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Concept
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Sequence Analysis, RNA
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Concept
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Genes, erbB-1
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Concept
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Genetic Predisposition to Disease
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Epigenesis, Genetic
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Concept
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Molecular Dynamics Simulation
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Academic Article
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p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
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Academic Article
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Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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BCR/ABL induces multiple abnormalities of cytoskeletal function.
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Academic Article
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The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
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Academic Article
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Role of focal adhesion proteins in signal transduction and oncogenesis.
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Academic Article
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The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
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Academic Article
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Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
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Academic Article
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Molecular abnormalities in lung cancer.
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Academic Article
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Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines.
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Academic Article
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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.
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Academic Article
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Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.
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Academic Article
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BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.
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Academic Article
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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
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Academic Article
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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
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Academic Article
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Molecular alterations in lung cancer. Impact on prognosis.
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Academic Article
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Small cell lung cancer: from molecular biology to novel therapeutics.
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Academic Article
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Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer.
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Academic Article
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Molecular biology of malignant mesothelioma: a review.
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Academic Article
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Recent advances in the molecular biology, diagnosis and novel therapies for various small blue cell tumors.
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Academic Article
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Lung carcinoma in African Americans.
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Academic Article
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PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
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Academic Article
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Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.
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Academic Article
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Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis.
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Academic Article
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Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer.
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Academic Article
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Expression and mutational analysis of MET in human solid cancers.
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Academic Article
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EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
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Academic Article
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Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
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Academic Article
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PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
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Academic Article
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Ethnic differences and functional analysis of MET mutations in lung cancer.
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Academic Article
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Fyn: a novel molecular target in cancer.
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Academic Article
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Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.
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Academic Article
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Pathologic response rates following definitive dose image-guided chemoradiotherapy and resection for locally advanced non-small cell lung cancer.
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Academic Article
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Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.
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Academic Article
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Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.
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Academic Article
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Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
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Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
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Academic Article
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A novel classification of lung cancer into molecular subtypes.
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Academic Article
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Differential expression of RON in small and non-small cell lung cancers.
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Academic Article
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
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Academic Article
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The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization.
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Academic Article
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Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
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Academic Article
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Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions.
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Academic Article
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c-Met is a potentially new therapeutic target for treatment of human melanoma.
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Academic Article
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CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells.
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Academic Article
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The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
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Academic Article
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MET molecular mechanisms and therapies in lung cancer.
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Academic Article
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Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
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Academic Article
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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
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Academic Article
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Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
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Academic Article
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Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells.
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Academic Article
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Detection and analysis of lung cancer cells from body fluids using a rare event imaging system.
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Academic Article
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Molecular and cellular biology of small cell lung cancer.
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Academic Article
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Key signaling pathways and targets in lung cancer therapy.
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Academic Article
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C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
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Academic Article
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Phase II study of amrubicin as second-line therapy in patients with platinum-refractory small-cell lung cancer.
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Academic Article
|
Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung.
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Academic Article
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Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
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Academic Article
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Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
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Academic Article
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Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
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Academic Article
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
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Academic Article
|
Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
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Academic Article
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Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
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Academic Article
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Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
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Academic Article
|
Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.
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Academic Article
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Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
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Academic Article
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Molecular biomarkers for future screening of lung cancer.
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Academic Article
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Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic.
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Academic Article
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Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.
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Academic Article
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Brain metastases in non-small-cell lung cancer: better outcomes through current therapies and utilization of molecularly targeted approaches.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Molecular pathways and therapeutic targets in lung cancer.
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Academic Article
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Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
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Academic Article
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A personalized treatment for lung cancer: molecular pathways, targeted therapies, and genomic characterization.
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Academic Article
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Molecularly targeted therapies in non-small-cell lung cancer annual update 2014.
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Academic Article
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Diagnostic challenges in non-small-cell lung cancer: an integrated medicine approach.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
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Academic Article
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Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.
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Academic Article
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
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Academic Article
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Systemic therapies in the treatment of non-small-cell lung cancer brain metastases.
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Academic Article
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Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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Tumor Heterogeneity and Therapeutic Resistance.
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Academic Article
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Mutation testing for directing upfront targeted therapy and post-progression combination therapy strategies in lung adenocarcinoma.
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Academic Article
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Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation.
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Academic Article
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FAK and paxillin, two potential targets in pancreatic cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.
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Academic Article
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Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
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Academic Article
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A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
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Academic Article
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Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
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Academic Article
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Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
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Academic Article
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Correction: AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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The Genetic/Non-genetic Duality of Drug 'Resistance' in Cancer.
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Academic Article
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Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.
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Academic Article
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EphB4: A promising target for upper aerodigestive malignancies.
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Academic Article
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Managing Patients With Relapsed Small-Cell Lung Cancer.
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Academic Article
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Untying the gordion knot of targeting MET in cancer.
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Academic Article
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B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
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Academic Article
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Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.
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Academic Article
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Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level.
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Academic Article
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Correction: Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-negative Breast Cancer.
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Academic Article
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Optimal adjuvant therapy in clinically N2 non-small cell lung cancer patients undergoing neoadjuvant chemotherapy and surgery: The importance of pathological response and lymph node ratio.
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Academic Article
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Notch signaling in breast cancer: From pathway analysis to therapy.
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Academic Article
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SOX9: The master regulator of cell fate in breast cancer.
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Academic Article
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Presence and structure-activity relationship of intrinsically disordered regions across mucins.
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Academic Article
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Precision medicine and actionable alterations in lung cancer: A single institution experience.
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Academic Article
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Association of TGF-ß1 Polymorphisms with Breast Cancer Risk: A Meta-Analysis of Case-Control Studies †.
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Academic Article
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Radiomic prediction of mutation status based on MR imaging of lung cancer brain metastases.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
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Academic Article
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Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors.
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Academic Article
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MET receptor in oncology: From biomarker to therapeutic target.
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Academic Article
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A Non-genetic Mechanism Involving the Integrin ß4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
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Academic Article
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Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease.
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Academic Article
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Erratum: A Non-genetic Mechanism Involving the Integrin ß4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
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Academic Article
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Integrating Academic and Community Cancer Care and Research through Multidisciplinary Oncology Pathways for Value-Based Care: A Review and the City of Hope Experience.
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Academic Article
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Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP.
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Academic Article
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The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC).
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Academic Article
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Group Behavior and Emergence of Cancer Drug Resistance.
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Academic Article
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Quantifying Cancer: More Than Just a Numbers Game.
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Academic Article
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Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy.
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Academic Article
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RNA-based therapies: A cog in the wheel of lung cancer defense.
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Academic Article
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Germline mutations and age at onset of lung adenocarcinoma.
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Academic Article
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Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.
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Academic Article
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Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer.
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Academic Article
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Molecular and Clinical Features of Hospital Admissions in Patients with Thoracic Malignancies on Immune Checkpoint Inhibitors.
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Academic Article
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AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer.
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Academic Article
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Addressing the genetic/nongenetic duality in cancer with systems biology.
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Academic Article
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Clinical and Molecular Features of KRAS-Mutated Lung Cancer Patients Treated with Immune Checkpoint Inhibitors.
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Grant
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ABNORMALITIES OF MOTILITY OF CML CELLS
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Grant
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Role of Paxillin in Lung Cancer
|
Grant
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MINIMAL RESIDUAL TUMOR IN SMALL CELL LUNG CANCER
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Grant
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Novel Targeted Therapy in Pancreatic Cancer
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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Academic Article
|
Twelve-Month Follow-up of the Immune Response After COVID-19 Vaccination in Patients with Genitourinary Cancers: A Prospective Cohort Analysis.
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Academic Article
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Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer.
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Academic Article
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A Nexus between Genetic and Non-Genetic Mechanisms Guides KRAS Inhibitor Resistance in Lung Cancer.
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